Cooper, K. L., G. M. Badalato, and M. P. Rutman. "Infections of the urinary tract." Campbell-Walsh-Wein Urology. 12th ed. Elsevier (2020): 1129-1201.
Cooper, K. L., G. M. Badalato, and M. P. Rutman. "Infections of the urinary tract." Campbell-Walsh-Wein Urology. 12th ed. Elsevier (2020): 1129-1201.
Antibiotic | Normal Dosing | Side Effects | Tips |
Nitrofurantoin (Macrobid) | 100mg BID | GI effects Peripheral neuropathy Hemolysis if G6PD Pulmonary hypersensitivity reaction (rare) |
Only works well for GU infections (not tissue) Don't give if GFR < 50 (inadequte excretion) Caution in elderly patients Do not take with quinolones, Mg, or probenecid |
Trimethoprim-Sulfamethoxazole (Bactrim) | Double-Strength (800/160mg) BID | Rashes GI effects Hyperkalemia Stevens Johnson syndrome (rare) |
Avoid in pregnancy Can exacerbate effects of warfarin |
Fosfomycin | 3g sachet x1 | Headache GI effects Vaginitis |
Not used frequently in US due to cost ($70-90) |
Ciprofloxacin (Cipro) Levofloxacin (Levaquin) |
500mg BID 250mg BID or 750mg daily |
GI effects, dizziness, photosensitivity CNS effects Tendon rupture |
Avoid in children or pregnancy Decreased oral absorption with iron, zinc, or antacid (separate by 2hrs) Can lower seizure threshold |
Cefuroxime Cefoxitin |
Do not use if patient has prior immediate hypersensitivity to penicillins Use with caution if delayed hypersensitivity to penicillins |
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Ampicillin (w/ Sulbactam) | 875/125mg BID | Hypersensitivity rash Diarrhea |
Rash more likely when viral disease present |
Cooper, K. L., G. M. Badalato, and M. P. Rutman. "Infections of the urinary tract." Campbell-Walsh-Wein Urology. 12th ed. Elsevier (2020): 1129-1201.
Cooper, K. L., G. M. Badalato, and M. P. Rutman. "Infections of the urinary tract." Campbell-Walsh-Wein Urology. 12th ed. Elsevier (2020): 1129-1201.