Strictures
Preop planning
Excision and Primary Anastomosis
- Place patient in dorsal lithotomy, prep/drape, give antibiotics (cefazolin +/- gentamicin)
- Make midline perineal incision, divide underlying layers, place lone star retractor
- Divide bulbospongiosus with metzenbaum scissors, identify urethra
- Circumferentially free urethra proximally and distally to allow for adequate mobilization
- Place cystoscope to identify stricture and mark site with cautery on outside of urethra
- Place 3 clamps - two at distal stricture site, then 3rd clamp very proximal to control sponge bleeding
- Cut urethra with heavy scissors
- Continue to remove strictured urethra until it accommodates 22-26Fr bougie, send urethra for pathology
- Spatulate urethra - distal dorsally, proximal perineally
- Start placing 4-0 monocryl anastomotic stitches, starting at 12 on proximal urethra and moving counterclockwise, with tails out outside
- Tip: place catheter after 6 o'clock stitch, ensuring it does not tangle the already-placed sutures and that the new sutures don't tag the catheter
- Tip: place dorsal stitches full thickness (9 to 3), place ventral stitches only through mucosa and not the spongiosum (8 to 4)
- After all stitches placed, tie down starting with 12 o'clock and moving counterclockwise, tying in order, confirm catheter is still mobile
- Close ventral spongiosum with 5-0 PDS running stitch
- Close bulbospongiosus and colles with 2-0 monocryl running, then close skin with 4-0 monocryl horizontal mattress interrupted, then place bacitracin, telfa, and dressing
Dorsal onlay buccal mucosa graft
- Position patient in high lithotomy position, shave perineum
- Give 1st/2nd gen cephalosporin, alternatively gentamicin + clindamycin
- Place buttock drape, staple towel across anus (to protect field), then drape legs and perineum (cut drape to access suprapubic region if needed
- Perform flexible cystoscopy, place wire through stricture (if able) into bladder to palpate in urethra
- Made midline incision along perineum with #15 blade, can extend anteriorly to scrotum
- Place Lone Star retractor (larger circle on perineum) and place hooks to retract skin, larger rakes for scrotal retraction
- Divide further layers down to bulbospongiosus, continue to reposition hooks, then divide bulbospongiosus
- Choose one side of urethra and divide urethra from surrounding tissue until dorsal portion is accessible
- Place 22Fr Bougie through meatus to level of distal stricture, mark urethra and start dorsal incision 1cm distal
- Incise further proximal until able to pass 22-28Fr Bougie, then perform cystoscopy to confirm no bladder abnormalities, can retract urethra with 4-0 vicryl retracting stitches through urethral edge
- Take fenestrated graft and suture (with 4-0 vicryl) at 5, 6, and 7 o'clock at proximal portion of graft, suture graft directly to urethra, then suture distal apex to hold in place
- Place 4-0 vicryl interrupted sutures on both edges - on side with native urethra, suture urethral edge + corpus underneath + graft edge
- Place 6-0 monocryl on TF needle in running fashion to quilt graft and hold it onto corpus, be careful not to wrinkle or tug on graft
- Place running 5-0 PDS on urethral edge, include corpus underneath
- Place catheter and run 5-0 PDS x2 from top and bottom to close urethra completely
- Close bulbospongiosus with 4-0 vicryl, then close overlying layers in two layers
- Close skin with interrupted horizontal mattress 3-0 monocryl suture, then place bacitracin
- Can discharge home with catheter same day
- Perform RUG in 3 weeks at time of catheter removal to assess for extravasation
Inflatable Penile Prosthesis
Penoscrotal approach
- Position in supine position, shave with razor if available (preferred over clippers)
- Prep and drape, use iodine sticky drape to decrease infectious risk - large half over superior portion of drape, smaller half as X shape to close hole between legs posterior to scrotum
- Give vancomycin + gentamicin (5mg/kg ideal body weight)
- Place 14Fr catheter into urethra, minimize lubrication
- Place Lone Star retractor with small loop inferiorly and white connector across behind infrapubic region, place hook into urethra to retract superiorly
- Perform ~2-3cm penoscrotal transverse incision, dissect through dartos, place 6 hooks for retraction
- Identify urethra and bluntly dissect laterally to identify corpora
- Protecting urethra, place 2-0 PDS stitch ~5mm lateral to urethra in corpora in proximal-to-distal fashion, snap/cut, then repeat ~1cm further lateral (repeat more proximally to create 4 stitches total)
- With #15 scalpel on finger, incise between stitches longitudinally, going 5mm proximal to stitch all the way to distal point of stitch
- Use #11 dilator distally and #13 proximally, aim laterally to avoid urethral injury, measure corpora and perform goal-post test (dilators in proximal corpora should not cross), irrigate to confirm no urethral injury
- Prepare appropriate size device
- Thread Keith needle and load urethrotome, pass distally and pass needle through glans (grab w/ hemostat), feed distal portion of prosthesis into corpus and secure stitch to retractor
- Place proximal end into corpus and use placement tool to secure and seat device
- Once device seated, tie proximal ends of stitch over a finger x8, then tie distal ends securely under tension to avoid prosthesis herniation or incisional bleeding
- Once prosthesis secured bilaterally, test inflate to ensure adequate placement and length
- Identify external inguinal ring, place plastic retractor, pop through with finger to enter retropubic space of Retzius, place retractor further interior, then place reservoir and inflate (waist should fill inguinal ring without herniating
- Grasping lateral and inferior incisional edges, create subdartos pouch and dilate with nasal speculum, then place pump into pouch
- Cut excess tubing length, fill ends with water, and secure connector
- Close inferior dartos hole vertically then close incisional dartos hole horizontally (both with 3-0 vicryl)
- Close skin with 4-0 monocryl interrupted fashion
- Place bacitracin ointment then provide mummy wrap
5-step high submuscular technique for reservoir placement
- Place patient in trendelenberg position
- Palpate external inguinal ring and place pediatric Deaver retractor
- Create submuscular tunnel above transversalis using finger blunt dissection, avoid widening neck (will prevent balloon prolapse)
- Place sponge stick, aim medial (towards ipsilateral nipple, keeps pocket deep to rectus)
- Ensure pocket is ≥ 10cm
- Insert reservoir via clamp, overfill to 120mL, then compress
- Palpate to ensure device is not too deep or too lateral
Peyronie's disease
Penile plication
- Once patient intubated, position supine and inject 20ug alprostadil in 1mL sterile water (do not use saline), inject into lateral corpus
- Prep, drape, give cefazolin, and place catheter (capped)
- Assess penile curvature, making longitudinal incision opposite maximal curvature (ventral midline if dorsal curvature only)
- Incise layers down to tunica albuginea over corpora, taking care to avoid urethra
- Use small retractors to assess corpora, choose proximal and distal areas at point of maximal bulge
- Place non-absorbable braided stitch in a 2-1-4-3 fashion, tie down to bury the knot
- After placing 3-4 stitches, assess erection for residual curvature
- Close deep layers x2 with monocryl or vicryl then close skin with subcuticular 4-0 monocryl, apply dermabond, telfa, and compressive dressing
Circumcision
Potential benefits
- There are no absolute medical indications for circumcision
- Cancer: penile cancer extremely rare in men after neonatal circumcision
- UTI: 20x increased risk, but requires 85-111 boys get circumcised to prevent 1 UTI
- HIV: reported benefits in subSaharan Africa, questionable benefit in US/Europe
- Hygiene: prevents phimosis, balanitis
Contraindications
- Do not perform if foreskin will be needed for future reconstructive procedures - hypospadias, chordee, buried/webbed penis
- Delay if concern for coagulopathy or other more urgent medical issues
Complications
- Bleeding: 0.1%, usually from a frenular blood vessel, can treat with silver nitrate or suture
- Wound infection: rare, can prophylactically treat with bacitracin
- Skin dehiscence: rare, self-resolves with shaft epithelization, does not require repair
- Skin abnormalities: rare, requires repair under general anesthesia
- Scarring: treat with 0.05% betamethasone + retraction, improves scar in 79%
- Skin bridges: common (more with younger age), lyse in clinic (with EMLA) or OR (may require suturing), do not resolve with steroids alone
- Inclusion cysts: uncommon, due to trapped epithelial tissue under scar, can use steroid cream to thin the skin or drain with small incision
- Meatal stenosis: common after circumcision, may present with upward or narrow stream, treat with meatotomy or meatoplasty, can use fine suture to reduce risk of recurrence
- Glans amputation: rare, repair via primary reanastomosis without microscopic repair, good results if performed within 8 hours
- Necrosis: prevent by avoiding thermal injury from cautery
- Fistula: rare, can occur if injury to urethra occurs
Postoperative care
- Depending on patient age and habitus, may benefit from gently retracting shaft skin to prevent adhesions
- Usually dressing can be removed after 24hr, may benefit from applying bacitracin or vaseline to incision
- Usually avoid physical activity for 2-3 weeks, avoid sexual activity for 6 weeks
Adult OR technique
- Place patient supine, prep/drape (clean under foreskin), give cefazolin for skin flora
- Give dorsal penile and ring block
- Place glans traction stitch with 2-0 silk (place deep to avoid tearing)
- Mark distal and proximal incisions, ensure adequate length by tensioning skin at base
- Gently incise skin with #15 scalpel, make sure skin separates but do not go through underlying layers
- Place mosquito snaps x4 on dorsal skin, then create tunnel with metzenbaum scissors and incise skin to create flaps
- Completely excise skin off penis with electrocautery, taking care not to cauterize remaining penile skin or shaft, send skin for specimen if needed
- Obtain hemostasis with point cautery
- Reapproximate frenulum with U-stitch (can use chromic or monocryl)
- Place stitches at 6, then 3 and 9 o'clock
- Close remaining skin edges with either simple or horizontal mattress interrupted
- Apply bacitracin, telfa, and coban dressing
Gomco technique
- Place on circumcision board
- Inject ~5mL 1% lidocaine as dorsal penile block, sit for 5 minutes
- Dilate phimotic ring with hemostat
- Crush foreskin at 12 o'clock position then cut to expose glans
- Remove all smegma and adhesions to fully expose glans
- Place hemostat x2 on the corners of the cut foreskin and place bell within foreskin on top of glans
- Place outer device over foreskin, grasp corners with new hemostat to bring the foreskin up and through device
- Confirm adequate and even position of Gomco device prior to tightening
- Leave for 5 minutes after tightening, can cut off foreskin at any time
- After 5 minutes, remove device and gently push edges off bell to expose penis
- Apply bacitracin and dressing
Pediatric OR technique #1
- Supine positioning
- Take down adhesions with a snap and sponge, sterilize with betadyne
- Demarcate proximal border, make incision w/ #15 scalpel
- Demarcate distal border, make incision w/ #15 scalpel
- Use 4 snaps to grap foreskin at dorsal aspect
- Spread with tenotomy scissors, cut at dorsal aspect
- Remove foreskin with cautery, discard unless abnormal appearing
- Obtain hemostasis of any active or potential bleeding
- Place two 5-0 stitches at ventral portion
- Reapproximate frenulum if necessary with simple interrupted
- Suture subcutaneous at 12 o’clock with 6-0, then perform running subcuticular dorsal to ventral, perform on either side
- At ventral portion, put stitch through skin, then go back through skin again and tie to loop
- Place mastisol, telfa strip, and tegaderm with cut on ventral then dorsal portion
- Cover with bacitracin
- Send home with tylenol, ibuprofen, and bacitracin
Pediatric OR technique #2
- Supine positioning
- Take down adhesions, sterilize with betadyne
- Demarcate proximal border, make incision w/ #15 scalpel
- Demarcate distal border, make incision w/ #15 scalpel
- Use 4 snaps to grap foreskin at dorsal aspect
- Spread with tenotomy scissors, cut at dorsal aspect
- Remove foreskin with cautery, discard unless abnormal appearing
- Obtain hemostasis of any active or potential bleeding
- Place 12 6-0 chromic stitches simple interrupted
- Place mastisol, telfa strip, and tegaderm with cut on ventral then dorsal portion
- Send home with tylenol and ibuprofen
Pediatric OR technique #3
- Supine positioning
- Take down adhesions, no betadyne
- Place 5-0 prolene stitch in glans for positioning
- Demarcate borders, incise with electrocautery on cut (or coag)
- Use 4 snaps to grap foreskin at dorsal aspect, spread with tenotomy scissors, cut at dorsal aspect
- Can also just cut through foreskin and take down in parts
- Remove foreskin with cautery, discard unless abnormal appearing
- Obtain hemostasis of any active or potential bleeding
- Place 12 o’clock stitch and 6 o’clock stitch and hold on with snaps (5-0 fast gut)
- Place 8 stitches total with 5-0 fast gut
- Place dermabond
- Send home with tylenol and ibuprofen
Dorsal Slit at bedside
- Perform dorsal penile and ring block, prep/drape
- Crush preputial skin at 12 o'clock with straight hemostat then incise - take care not to insert hemostat into meatus!
- If necessary, retract skin and continue to crush/cut until glans of penis completely exposed
- Suture edges with 3-0 or 4-0 chromic as running or interrupted stitch to provide hemostasis
Phalloplasty (for buried penis)
- Prep/drape, perform dorsal penile and ring blocks
- Take down all adhesions and clean smegma to visualize entire penis, then place 4-0 ethibond traction stitch
- Demarcate the inner preputial incision by drawing a circumferential line, then incise with #15 scalpel
- Deglove the penis down to the base, exposing edges and using cautery or tenotomy to cut attachments
- Assess where skin will comfortably lie on the shaft, then cut the dorsal skin at 12 o'clock with tenotomy until a point where it will come together with the glans edge
- Place fixation sutures at 12, 5, and 7 o'clock to fix shaft skin to penile base, bury the knots, use 5-0 PDS (or similar suture)
- Wrap dorsal skin flaps around ventrally for coverage and excise the excess tissue
- Realign ventrally, recreate frenulum and raphe as needed to bring skin together without tension
- Bring circumcising incision together through desired technique (running/interrupted)
- Apply dermabond and dressing, remove traction stitch
Hypospadias
Preoperative considerations
- Indications: allow for normal urination, erection (fix chordee), and ejaculation
- Consider repair timing, usually 6-18mo to prevent patient anxiety regarding genitals and complications
- Preoperative testosterone: consider if small glans, give IM testosterone 5 and 2 weeks prior to surgery
Repair tips/techniques
- Goals: create normal meatus/glans, straighten penis, normal urethra, adequate skin covering, normalize scrotum position
- Urethromeatoplasty: use Heineke–Mikulicz technique for stenotic distal meatus
- Primary tubularization (GAP, Thiersch-Duplay): use glans wings to tubularize without incising urethral plate
- Meatal advancement glanuloplasty (MAGPI): advances the distal glans without tubularizing
- M inverted V glansplasty (MIV): parameatal skin is compliant for glanuloplasty
- Tubular incision (TIP): incise plate and tubularize using glans wings to increase diameter
- Proximal repairs usually require staging and urethral flaps/grafts
Postoperative management
- Leave a urethral stent in place for 3-21 days, SPT occasionally used
- Antibiotic prophylaxis and anticholergics used depending on circumstances
- Follow-up: 4-6 weeks after surgery, then 1yr postop, after toilet training, and after puberty to assess for complications and discuss concerns
Hypospadias complications
- Fistula: 4-28%, may present with double stream, management depends on specific situation
- Glans dehiscence: 0-8%, separation of glans wings, repair depends on presence of symptoms
- Meatal stenosis: 0-14%, obstructive voiding symptoms, warrant repair or dilation
- Urethral stricture: 6-12%, usually form at junction of urethra and neourethra, warrants repair
- Urethral diverticulum: urethral ballooning with voiding, warrants repair
- Recurrent curvature: 9-32%, > 30 degrees demonstrated on erection
- Secondary phimosis: 2-20%, treat with circumcision
- Urethral stones: 5-15%, due to flap with hair-bearing skin, can ablate hair or perform substitution urethroplasty
Penile curvature (chordee)
- Assess intraoperatively after degloving, use goniometer while injecting saline
- 30 degree cutoff used for dorsal plication vs dividing urethra (corporal lengthening)
- Usually plicate at 12 o'clock, avoiding neurovascular bundles
- Important to repair curvature, otherwise will worsen during puberty
Penile torsion
- Seen in 2-27% males, > 90% torsion seen in 0.7%
- Can observe (usually asymptomatic), consider treating if affecting urination or intercourse (uncommon)
Tubularized incision of plate (TIP) technique
- Can perform penile block or caudal block (some concern that caudal block increases risk for fistula formation)
- Position supine, prep/drape, can give cefazolin or other antibiotic due to urethral manipulation
- Take down preputial adhesions to assess foreskin length and location, assess degree and direction of curvature
- Place ethibond traction stitch into glans, place 8Fr feeding tue
- Perform dorsal circumcision incision, extend laterally to create Firlit wings (inner preputial wings), then extend ventraly taking care over urethra
- Deglove the penis, create an artificial erection to assess curvature
- Can perform plication stitches dorsally if necessary due to curvature (will worsen during puberty)
- Apply tourniquet with umbilical tape when performing glansplasty to minimize bleeding
- Incise urethral place at midline from glans down to meatus, use wescott scissors or small scalpel
- Create glans wing incisions on either side of urethra, then close with running 7-0 PDS in two layers
- Using excess dorsal dartos, create dartos flap (remove overlying skin), create buttonhole and place over penis so that flap lies ventrally, then secure over urethroplasty with 7-0 interrupted PDS
- Complete glansplasty with 5-0 PDS horizontal mattress sutures and epithelial 7-0 vicryl
- Exchange 8Fr feeding tube for 7Fr stent, stitch to glans to ensure it stays in place
- Assess and adjust skin for coverage, and place fixation stitches at penopubic and penoscrotal junctions at 12, 5, and 7 o'clock
- Complete circumcision, bring flaps around for adequate coverage, close with interrupted 5-0 plain gut (can perform simple or subcuticular interrupted)
- Apply circumferential telfa dressing, then tegaderms to hold in place
- Remove dressing POD#4, remove catheter POD#7, prophylactic antibiotics until POD#9
References
- Baskin, Laurence S. Handbook of pediatric urology. Lippincott Williams & Wilkins, 2018.
- Long, C., M. Zaontz, and D. Canning. "Hypospadias." Campbell-Walsh Urology 12 (2020).